Stratonice (Greek: Στρατoνίκη) of Syria was the daughter of king Demetrius Poliorcetes and Phila, the daughter of Antipater. In 300 BCE, when she was probably about 17 years old, her hand was solicited by Seleucus, king of Syria, and she was conducted by her father Demetrius to Rhosus, on the Pierian coast in Macedonia, where her nuptials were celebrated with the utmost magnificence. Despite their age difference, Stratonike seems to have had a harmonious relationship with her husband, and she bore him a daughter,called Phila.
However, an uncomfortable situation arose within the royal family. Antiochus, Seleucus' son from Apama, had fallen deeply in love with Stratonice. His feelings were so strong,that his health had begun to decline badly. In order to protect his son's life, Seleucus gave up Stratonice in marriage to the young Prince in 294 BCE. At the same time, he made Antiochus King of the Eastern provinces. This somewhat awkward union between Stratonice and Antiochus seems to have been prosperous; however, we find little information about the Queen herself after that.The evidence available informs us that she had five children with Antiochus and that the city of Stratonikeia in Caria was named after her by Antiochus.
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